· PI (Physik Instrumente) LP
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How Fast Nano-Focusing and Z-Scanning Mechanisms Advance Life Sciences, Biotech, Laser Processing, and Semiconductors
Linear Motors and Piezo Drives Solve Different Problems

Optical Delay Lines and Delay Line Stages – How Do They Work?
Turning Nanometers into Femtoseconds and Attoseconds

High Dynamic and Precision in All Three Directions in Space: Positioning Systems for Genome Sequencing
· Dr. Thomas Bocher · Markus Wiederspahn
The Sequencing-by-Synthesis method, also known as Solexa-Illumina-method, is the most widespread method among all Next-Generation-Sequencing methods (NGS). It was used to identify the RNA fingerprint of the SARS-COV2 virus in January 2020 in a research institute in Wuhan. Dynamic and precise motion and positioning systems are crucial for the "Sequencing-by-Synthesis" genome sequencing method.
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PI Motion Platforms & Microscopy: Key Principles
Nanometer Resolution for SNOM, AFM, SR-Microscopy
· PI (Physik Instrumente) LP
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Optical Tweezers with XYZ-Piezo Nanopositioning Stages
· PI (Physik Instrumente) LP
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Piezo Flexure Stages and Piezo Shear Actuators in Ion Conductance Microscopy
· PI (Physik Instrumente) LP
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Nano-Positioning Systems for Atomic Force Microscopy (AFM)
· PI (Physik Instrumente) LP
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Quantitative Measurement of Protein Dynamics with High Linearity Atomic Force Spectrometer
· PI (Physik Instrumente) LP
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Flamingo Light Sheet Microscopes Rely on Drives from PI
Precise Sample Positioning is Crucial for Conclusive Images
· Markus Wiederspahn · Dr. Thomas Bocher
Lightsheet microscopy (LSFM) is a powerful platform for in vivo imaging offering low phototoxicity and fast image acquisition. The Flamingo project from Professor Dr. Jan Huisken, Research Group Leader and Director of the Medical Engineering Department at Morgridge Institute for Research in Madison, WI, aims to make this technology easily available to researchers.
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How Nanopositioning Mechanisms Improve Performance of High Resolution Microscopy in DNA-Origami, DNA-Paint and TIRF Techniques
· PI (Physik Instrumente) LP
Nano-positioning mechanisms (such as piezoelectric lens movers, precision linear XY stages and Z-stages) increase performance and/or speed of different high-resolution microscopy techniques.
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